Table 1.

Operational criteria for identification of physical prefrailty in the My-AHA project

Physical domain
Prefrail = 1 or 2 of the following criteria are met
1. Shrinking, evidenced by weight loss (unintentional)	≥4.5 kg unintentional in prior 12 months; or at follow-up assessment ≥ 5% of body weight in prior 12 months	Self-reported weight loss (not due to dieting or fasting) in preceding 12 mo ≥ 4.5 kg Follow-up: K = (weight in previous year–current measured weight)/(weight in previous year). If K ≥ 0.05, meets weight loss frailty criteria
2. Weakness	Grip strength in lowest 20% at baseline adjusted for gender and BMI

	Males	BMI	Grip strength (kg)	Females	BMI	Grip strength (kg)
		≤24	≤29		≤23	≤17
		24.1–26	≤30		23.1–26	≤17.3
		26.1–28	≤30		26.1–29	≤18
		>28	≤32		>29	≤21

3. Poor endurance and energy	Self-report of exhaustion as indicated by responses to two questions on CES-D scale	Using the CES–D Depression Scale, response of “2” (a moderate amount of the time, 3–4 days) or “3” (most of the time) to either of the following 2 items: (a) I felt that everything I did was an effort; and/or (b) I could not get going.
4. Slowness	Time to walk 4.00 m ≤ slowest 20% adjusted for gender and standing height

	Male	Height (cm)	Time to walk 4 m	Female	Height (cm)	Time to walk 4m
		≤173	≥6.13 sec		≤159	≥6.13 sec
		>173	≥5.25 sec		>159	≥5.25 sec

5. Low physical activity level

Energy expenditure per week below established cutoff

Short version of the IPAQ questionnaire assesses activity levels for walking, moderate-intensity and vigorous-intensity activities for work, transportation, domestic chores, gardening, and leisure-related activities.

IPAQ activity category level = low

Abbreviations: My-AHA, My Active and Healthy Aging; IPAQ, International Physical Activity Questionnaire; CES-D, Center for Epidemiologic Studies Depression Scale; BMI, body mass index.