Table 2.

Summary of Assay Results for Uridine-Depleted Sequences

	WT UD	WT UD HPLC	5moU UD	5moU UD HPLC	Ψ UD	Ψ UD HPLC
High indel	+	+	+	+	+	+
Lack of IFN in THP-1 Dual cells	–	+	+	+	–	+
Lack of IL-12 in whole blood	–	+	+	+	+	+
Lack of TNF-α in whole blood	–	–	+	+	+	+
Lack of IL-12 in vivo	+	+	+	+	+	+
Lack of TNF-α in vivo	+	+	+	+	+	+