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. 2018 Aug 3;8:11654. doi: 10.1038/s41598-018-30185-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Gene and protein expression of MMP-1, and production of TIMP-2 as endogenous inhibitor of MMP-1, in NPM treated with PBM. (A) Production of MMP-1 at 630 nm, (B) 525 nm, and (C) 465 nm. (D) The relative gene expression of MMP1 at 630 nm, (E) 525 nm, and (F) 465 nm. (G) Production of TIMP-2 at 630 nm, (H) 525 nm, and (I) 465 nm. Values are mean ± SE of three or four independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 as compared with NP, and line indicates comparison with each group. ns, no significant difference.