Table 1.
Comparison of polymorphisms in primer annealing region of Bodmer group Primers and IARC primers and their MAFs.
| Primers used in the study (Bodmer group primers) | IARC primers | ||
|---|---|---|---|
| Number of Polymorphisms in PAR (MAF range)^ | Number of polymorphisms in PAR (MAF range)^ | ||
| 1 F | 1 (0.0007) | — | |
| 1 R | 3 (0.00003) | — | |
| 2 F | 2 (0.00003–0.0001) | — | |
| 2 R | 7 (0.00003–0.0002) | — | |
| 2–3 F | — | 2 (0.00002–0.00003) | |
| 2–3 R | — | 7 (0.000008–0.0853*) rs17883323 | |
| 3 + 4 F | 3 (0.000008–0.0012) | — | |
| 3 + 4 R | 2 (0.00003) | — | |
| 4 F | — | 7 (0.000008–0.0113*) rs35117667 | |
| 4 R | — | 2 (0.000008–0.0002) | |
| 2nd set | 4 F | — | 7 (0.000008-0.0853*) rs17883323 |
| 4 R | — | 1 (0.0001) | |
| 5 F | — | 4 (0.000009-0.0002) | |
| 5 R | — | 6 (0.000008-0.0002) | |
| 5 + 6 F | 2 (0.0018–0.0073) | 4 (0.00001–0.00003) | |
| 5 + 6 R | 10 (0.00001–0.0034) | 8 0.000009–0.0088) | |
| 6 F | — | 3 (0.00002) | |
| 6 R | — | 8 (0.000009–0.0088) | |
| 7 F | 4 (0.0001–0.0002) | 3 (0.000008–0.0002) | |
| 7 R | 3 (0.0001–0.178*) rs12951053 | 2 (0.00003) | |
| 2nd set | 7 F | — | 3 (0.00002–0.0127*) rs17880604 |
| 7 R | — | 5 (0.000008–0.0025) | |
| 8 F | — | 4 (0.00002–0.0013) | |
| 8 R | — | 3 (0.000008–0.0002) | |
| 8–9 F | 2 (0.0002) | 1 (0.0002) | |
| 8–9 R | 2 (0.000008–0.00002) | 3 (0.000008–0.0002) | |
| 9 F | — | 5 (0.000008–0.0002) | |
| 9 R | — | 3 (0.00002) | |
| 10 F | 6 (0.00001–0.0002) | 0 | |
| 10 R | 6 (0.00003–0.00007) | 1 (0.0016) | |
| 11 F | 1 (0.0002) | 3 (0.00002–0.0112*) rs17881850 | |
| 11 R | 4 (0.00007–0.0001) | 3 (0.0002–0.0014) | |
| Total | 58 | 98 | |
Legend: ^Range of highest Minor Allele Frequency (MAF) as reported in different databases like 1000 Genomes database, TOPMED, ExAC, as documented in dbSNP of all the polymorphisms in the primer annealing region of TP53. *The frequency of polymorphisms higher than 1% and their rs id.