Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) The luciferase assay was miniaturized to a 1536-well format. (b) Clone SB01 was used to screen approximately 6000 compounds from several libraries, including the LOPAC, NPC and MIPE collections. The average Z′ factor for the screen was 0.7. (c) A scatter plot of the screening results demonstrates how well this assay performed. Blue dots represent BRAF inhibitors, red dots represent MEK inhibitors, and green dots represent ERK inhibitors.
