Effect of the ERα agonist PPT on short-term (up to 4h) and daily (22-h) food intake in OVX rats (N=9). (A) At 1h, food intake was decreased by all but the lowest dose of PPT. At 2 and 4h, PPT produced a dose-dependent decrease in food intake. (B) Daily (22-h) food intake was decreased by the two highest doses of PPT (100 and 200μg/kg). *Less than vehicle, p<0.05. †Less than vehicle, 0.01, and 200μg/kg PPT.