Figure 2.

Volcano plots for the pair-wise comparison of patients developing cancer and patients not developing cancer

Volcano plots show on the Y-axis the negative log₁₀P value of the t-test and on the Y-axis the log₂ fold change. Green dots indicate miRNAs with higher expression in blood samples from Cohort 1, while red dots represent miRNAs with higher expression in blood samples from Cohort 2 according to the raw P < 0.05. All dots with raw P ≥ 0.05 are colored in gray. The horizontal blue line separates miRNAs that are significant following Benjamini–Hochberg adjustment (above the line; adjusted P < 0.05) and miRNAs that are not significant anymore following the adjustment (below the line).