Table 1.
Baseline Characteristics in Polycystic Ovary Syndrome Women With or Without Central Obesity
| Central obesity (n = 70) | Noncentral obesity (n = 118) | |
|---|---|---|
| No. of cycles | 70 | 118 |
| Age (years) | 30.2 ± 3.5 | 29.5 ± 3.5 |
| Duration of infertility (years) | 5.38 ± 3.28 | 4.76 ± 3.15 |
| Primary infertility (n, %) | 42 (60.0) | 72 (61.0) |
| Cause of infertility (n) | ||
| PCOS | 20 | 28 |
| PCOS and tubal factor | 38 | 64 |
| PCOS and male factor | 10 | 20 |
| PCOS and endometriosis | 2 | 6 |
| Times of cycle | 1.21 ± 0.41 | 1.16 ± 0.37 |
| PCOS phenotypes | ||
| HA, OAD, and PCOM | 39 (55.7) | 53 (44.9) |
| HA and OAD without PCOM | 13 (18.6) | 17 (14.4) |
| HA and PCOM with ovulatory cycles | 4 (5.7) | 16 (13.6) |
| OAD and PCOM without HA | 14 (20.0) | 32 (27.1) |
| BMI (kg/m2) | 24.9 ± 2.2* | 20.4 ± 2.4* |
| Waist circumference (cm) | 86.1 ± 6.2* | 71.0 ± 4.4* |
| Hip circumference (cm) | 97.5 ± 6.4* | 89.3 ± 4.2* |
| Waist–hip ratio | 0.88 ± 0.06* | 0.80 ± 0.05* |
| Basal FSH (IU/L) | 7.21 ± 2.82 | 7.32 ± 2.30 |
| Basal LH (IU/L) | 7.90 ± 5.13 | 8.09 ± 5.32 |
| Basal TT (nmol/L) | 2.03 ± 0.72 | 2.14 ± 0.87 |
| FT (pg/mL) | 3.92 ± 2.37 | 3.11 ± 2.35 |
| FAI | 5.73 ± 4.73* | 3.17 ± 2.47* |
| DHEA-S (ng/mL) | 2231.4 ± 983.6 | 2200.4 ± 1077.1 |
| SHBG (nmol/L) | 57.8 ± 44.8* | 103.4 ± 85.1* |
| Serum fasting glucose (mmol/L) | 5.35 ± 0.78** | 5.08 ± 0.44** |
| Serum fasting insulin (mU/L) | 11.63 ± 7.17* | 6.34 ± 3.63* |
| HOMA-IR | 2.87 ± 2.44* | 1.44 ± 0.84* |
| Insulin resistance (n, %) | 45 (64.3)* | 20 (16.9) * |
| 2-h glucose (mmol/L) | 8.38 ± 3.03* | 6.54 ± 2.14* |
| 2-h insulin (mU/mL) | 111.98 ± 68.36* | 64.26 ± 47.65* |
| IFG (n, %) | 17 (24.3)** | 14 (11.9)** |
| IGT (n, %) | 17 (24.3)** | 13 (11.0)** |
| Type II DM (n, %) | 8 (11.4) | 4 (0.3) |
| CHOL (mmol/L) | 5.11 ± 0.50 | 4.83 ± 0.90 |
| TG (mmol/L) | 2.70 ± 2.30* | 1.25 ± 0.65* |
| HDL-C (mmol/L) | 1.37 ± 1.35** | 1.52 ± 0.27** |
| LDL-C (mmol/L) | 3.10 ± 0.68 | 2.80 ± 0.85 |
| Volume of left ovary (mL) | 7.68 ± 5.92 | 7.23 ± 3.17 |
| Volume of right ovary (mL) | 7.46 ± 6.13 | 7.82 ± 4.34 |
| AFC | 25.8 ± 9.1 | 25.8 ± 8.5 |
Values are expressed as mean ± SD or numbers (percentages).
Significant differences between two groups, p < 0.01.
Significant differences between two groups, p < 0.05.
PCOS, polycystic ovary syndrome; PCOM, polycystic ovarian morphology; HA, hyperandrogenism; OAD, oligoanovulatory ovarian dysfunction; BMI, body mass index; FSH, follicle-stimulating hormone; LH, luteinizing hormone; TT, total testosterone; FT, free testosterone; FAI, free androgen index; DHEA-S, dehydroepiandrosterone sulfate; SHBG, sex hormone-binding globulin; HOMA-IR, homeostatic model assessment for insulin resistance; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; DM, diabetes mellitus; CHOL, cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; AFC, antral follicle count; SD, standard deviation.