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Frequent and Notable Grade ≥3 Adverse Events
| Type of Adverse Event |
Incidence (%) |
||
|---|---|---|---|
| Grade 3 | Grade 4 | Grade 5 | |
| Hypertension | 27 (24%) | 2 (2%) | 0 (0%) |
| Pain | 22 (20%) | 0 (0%) | 0 (0%) |
| Proteinuria | 8 (7%) | 0 (0%) | 0 (0%) |
| Nausea | 5 (4%) | 0 (0%) | 0 (0%) |
| Syncope | 3 (3%) | 0 (0%) | 0 (0%) |
| Cardiac Ischemia | 1 (1%) | 0 (0%) | 0 (0%) |
| Hemorrhage | 1 (1%) | 0 (0%) | 1 (1%) |
| Thrombosis | 1 (1%) | 0 (0%) | 0 (0%) |
| Hypocalcemia | 0 (0%) | 1 (1%) | 0 (0%) |
| Neutropenia | 0 (0%) | 1 (1%) | 0 (0%) |
| Other Neurologic Event | 0 (0%) | 1 (1%) | 0 (0%) |
