. Author manuscript; available in PMC: 2019 Sep 1.

Published in final edited form as: Breast Cancer Res Treat. 2018 May 22;171(2):325–334. doi: 10.1007/s10549-018-4828-5

Table 7.

Multivariable Models with Age

Risk Factors for Grade ≥3 Toxicity	OR (95% CI)	p-value	c-statistic
Age (≥65) Vision (fair or worse)	3.62 (1.30 – 10.09) 5.36 (1.10 – 26.29)	0.01 0.04	0.646
Age (≥65) Needing help getting to places out of walking distance^a	2.71 (0.96 – 7.69) 4.00 (0.81 – 19.74)	0.06 0.09	0.632
Age (≥65) Limitation in climbing flights of stairs^b	2.88 (1.02 – 8.16) 2.80 (1.24 – 6.35)	0.05 0.01	0.670
Age (≥65) Limitation in walking more than one mile^b	2.82 (1.00 – 7.97) 2.28 (1.01 – 5.32)	0.05 0.05	0.659

^a:

Instrumental Activities of Daily Living³²

^b:

Medical Outcomes Study³³