Experiment design (Experiment model; Venom; Assay; Test subject) |
Extract | Plant part | Plant Source | Extract dose; Route of administration | Result | Reference |
---|---|---|---|---|---|---|
in vitro; Heterometrus laoticus scorpion venom; Pre-incubated extract with 0.2 μg/μL venom-Cell lytic test incubated for 30 min; CEFs | Water | Leaf | Thailand | 0.706, 0.406 mg/mL | Extract at 0.706 mg/mL give 46.51% of efficiency but the cytotoxic of extract is questionable | [65] |
in vitro; Apis mellifera Linn. bee venom; Pre-incubated extract with 0.6 μg/μL venom-Cell lytic test incubated for 30 min; CEFs | Water, 90% and 50% ethanol | Leaf | Thailand | 0.706, 0.406 mg/mL | Ineffective | [66] |
in vivo; Laticauda colubrine snake venom; Mice and Mongrel dog | Water; Maceration | Leaf | Sarawak Malaysia |
6 mg/kg per mouse (i.p), 20 mg/kg per dog (i.v) | Ineffective | [7] |
in vivo; Naja naja siamensis snake venom; Isolated rat phrenic-nerve diaphragm preparations; Mice | Water | Leaf | Thailand | p.o, i.p | Ineffective | [5] |
in vivo; Snake venom; Mice | Water | Leaf | Thailand | - | Reduce mortality rate from 100% to 63 ± 3.34% | [67] |
in vivo; Snake venom; Mice | 95% alcohol | Leaf | Thailand | 2000 mg/kg; i.v, i.p, p.o | Ineffective | [67] |
CEFs: Chick embryo fibroblasts.