(o) Pharmacological activity: oral mucositis and stomatitis treatment

Experiment design  (Experiment model; Infection; Assay; Test subject; Route of administration/Prescription)	Extract	Plant Source	Positive control	Result	Reference
Clinical; Radiation induced oral mucositis; Single-blinded-Randomized trial; 60 patients; Apply 2 drops drip into mouth or on the lesion 3 to 5 times daily from first to last day of radiation	Glycerin payayor	Thailand	Benzydamine hydrochloride  (Difflam, 3M, Australia)	The time onset of oral mucositis in the payayor group was significantly later, and its severity and pain score were less than those of the benzydamine group throughout the study period.	[10]
Clinical; Reccurent aphthous stomatitis; Double-blinded-controlled trial; 43 patients; apply to the ulcer 4 times daily	C. nutans in orabase	Thailand	Triamcinolone acetonide, placebo	C. nutans in orabase provide better healing of the ulcer as compared to placebo but efficacy was lesser compared to triamcinolone acetonide in orabase	[91]