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. Author manuscript; available in PMC: 2018 Aug 5.
Published in final edited form as: Clin Cancer Res. 2018 Jan 23;24(8):1881–1890. doi: 10.1158/1078-0432.CCR-17-3103

Figure 1.

Figure 1.

ctDNA fraction estimated across gastrointestinal disease histologies. MSAF was used to estimate the ctDNA fraction in a given sample. MSAF was significantly greater for all gastrointestinal ctDNA cases versus gastric carcinoma ctDNA cases (*, P = 0.011) and in colorectal carcinoma ctDNA cases versus gastric ctDNA cases (**, P = 0.003). Box-and-whisker plots: box spans first and third quartiles, the median is denoted by the horizontal line in the box, and whiskers indicate maximum and minimum values within 1.5× the interquartile range.