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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: J Trauma Acute Care Surg. 2018 Nov;85(5):851–857. doi: 10.1097/TA.0000000000002022

Table 3.

Primary outcome measures

No-TXA
(n=62)
TXA
(n=31)
P
Mortality, %
  6-hours 34% 13% 0.04
  12-hour 36% 23% 0.24
  18-hour 39% 23% 0.16
  24-hour 39% 26% 0.25
  30-day 50% 45% 0.82
Transfusions in 24 hours, Units, median [IQR]
  RBC 12 [7–22] 15 [10–33] 0.11
  Plasma 10 [3–16] 15 [7–22] 0.03
  Platelets 10 [6–18] 13 [7–19] 0.13
Time to achieve hemostasis, min [IQR] 158 [87─243] 139 [86─255] 0.65
Re-bleeding requiring intervention, % 3.2% 9.7% 0.13
Cause of death, %
  Exsanguination/Hemorrhagic shock 32% 26% 0.39
  TBI 13% 10% 0.62
  Respiratory 1.6% 6.4% 0.26
  Other 3.2% 3.2% 1.00

Min=Minutes, IQR=Interquartile Range