Fig. 1.

Running Wheel activity in postnatal day (PND) 25 Long-Evans hooded male rats. (a) Mean hourly wheel rotations during light and dark phases over 2 days. G1: standard chow/RO-H₂O (n = 15); G2: low-F⁻ chow/RO-H₂O (n = 15); and G3: low-F⁻ chow/10 ppm F⁻ drinking water (n = 16). Drinking water exposure began on gestational day 6. (b) Mean hourly wheel rotations over 5 days (mean ± SEM) for G2 (n = 10) and G4: low-F⁻ chow/20 ppm F⁻ drinking water (n = 10). Shaded areas represent dark phase of elevated activity