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. 2018 Jul 30;12:62. doi: 10.3389/fnana.2018.00062

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Copyright © 2018 Imperatore, D’Angelo, Safari, Motlagh, Piscitelli, de Girolamo, Cristino, Varricchio, di Marzo and Paolucci.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of OX-2R (red) and CB1R (green), and their co-localization OX-2R/CB1R (yellow) in coronal sections of the midbrain. (A,B) OX-2R/CB1R co-expression has been observed in the optic tectum (TeO), along the tectal ventricle (TeV), TTB, dorsal (Hd) and central (Hc) zone of the periventricular hypothalamus, DIL. (A₁–A₅) Higher magnification of the fields boxed in (A) showing the OX-2R/CB1R co-expression within the TeO (A₁), TeV (A₂), TTB (A₃), Hd (A₄), Hc (A₅). (B₁) Higher magnification of the field boxed in (B) showing the OX-2R/CB1R co-expression within the DIL. DAPI (Blue) was used as a counterstaining to show nuclei. Va, Valvula Cerebelli. Scale bar, 250 μm for (A,B); 50 μm for (A₁–A₅,B₁).