Table 1.

Summary of the analyses supported in ASAP compared to other related webservers.

Feature	ASAP	BRepertoire	ARGalaxy	Vidjil	VDJviz	VDJServer
Paired-end alignment	+	−	+	+	−	+
VDJ annotation	+	−	+	+	−	+
Framework and CDR3 annotation	+	−	+	+	−	+
Filtering	+	−	+	+	−	+
Data trimming	+	−	+	+	−	+
Unique molecular identifier clustering	+	−	−	−	−	+
Inclusion of novel germline alleles	+	−	−	+	−	−
CDR3 length distribution	+	+	+	+	+	+
Somatic hypermutations level	+	−	+	−	−	+
Synonymous/non-synonymous mutations	+	+	+	−	−	+
Isotype distribution	+	−	+	−	−	−
Joint analysis for replicates	+	−	−	−	−	+
Clonal analysis	+	+	+	+	+	+
V(D)J usage	+	+	+	+	+	+
V-D-J combination analysis	+	+	+	+	+	+
Clone ranking detailed analysis	+	–	−	−	+	+
Integrative database of all unique variable region sequences including sequence metadata	+	–	−	−	−	−
MS ready database for proteomics analysis of secreted antibodies	+	–	−	−	−	−
Amino acid level sequences linked to nucleotide level	+	–	−	−	−	−
Single push-button for all analysis steps	+	–	+	−	−	−