Figure 1.

Course of Bordetella pertussis infection in azithromycin (AZM)-treated mice. C57BL/6 mice were infected by aerosol challenge with B. pertussis and treated with AZM on 7 or 14 days post challenge. The control group of mice received DMSO. The course of infection following a high (A) and a low (B) initial infection dose. The results are mean (±SEM) CFUs on lung homogenates for five mice per group at each timepoint. Statistical significances were determined via two-way ANOVA followed by Sidak’s multiple comparisons test, *p < 0.05, ***p < 0.001.