Table 1. Clinical and Histological Findings in Our Cohort (n=79).
| Granuloma | Non-granuloma | |||
|---|---|---|---|---|
| iTB (n=10) | CD (n=42) | iTB (n=10) | CD (n=42) | |
| Age (yr) | 29.5±9.6 | 29.75±6.7 | 42.9±12.0 | 36.4±13.2 |
| Age at diagnosis (yr) | ||||
| <16 | 2 (10.5) | 0 | 0 | 2 (4.8) |
| 17–40 | 15 (78.9) | 7 (87.5) | 6 (60.0) | 23 (54.8) |
| >40 | 2 (10.5) | 1 (12.5) | 4 (40.0) | 17 (40.5) |
| Sex | ||||
| Male | 10 (52.6) | 4 (50.0) | 6 (60.0) | 27 (64.3) |
| Female | 9 (47.3) | 4 (50.0) | 4 (40.0) | 15 (35.7) |
| Duration of the disease (mo) | 29.6±25.4 | 48.6±44.5 | 11±12.7 | 58.4±73.1 |
| Behavior of the disease (Montreal classification) | ||||
| Non-stricturing (B1) | 9 (47.3) | 4 (50.0) | 6 (60.0) | 26 (61.9) |
| Stricturing (B2) | 9 (47.3) | 4 (50.0) | 4 (40.0) | 13 (30.9) |
| Penetrating (B3) | 1 (5.2) | 0 | 0 | 3 (7.1) |
| Perianal disease (P) | 0 | 0 | 0 | 0 |
| Location of disease | ||||
| Ileal (L1) | 6 (31.5) | 2 (25.0) | 2 (20.0) | 12 (28.5) |
| Colonic (L2) | 5 (26.3) | 3 (37.5) | 2 (20.0) | 13 (30.9) |
| Ileocolonic (L3) | 7 (36.8) | 3 (37.5) | 6 (60.0) | 13 (30.9) |
| Isolated upper digestive (L4) | 1 (5.2) | 0 | 0 | 1 (2.4) |
| L1+L4 | 0 | 0 | 0 | 1 (2.4) |
| L2+L4 | 0 | 0 | 0 | 1 (2.4) |
| L3+L4 | 0 | 0 | 0 | 1 (2.4) |
| Site of biopsy | ||||
| Rectum | 1 (5.2) | 0 | 0 | 1 (2.4) |
| Rectosigmoid | 0 | 0 | 0 | 2 (4.7) |
| Sigmoid | 0 | 0 | 0 | 2 (4.7) |
| Descending colon | 0 | 0 | 1 (10.0) | 2 (4.7) |
| Transverse colon | 3 (15.7) | 2 (25.0) | 0 | 4 (9.5) |
| Ascending colon | 1 (5.2) | 1 (12.5) | 1 (10.0) | 6 (14.2) |
| Caecum | 1 (5.2) | 0 | 1 (10.0) | 2 (4.7) |
| Ileocaecal | 9 (47.3) | 2 (25.0) | 4 (40.0) | 8 (19.1) |
| Terminal Ileum | 3 (15.7) | 3 (37.5) | 3 (30.0) | 15 (35.7) |
| Gastric | 1 (5.2) | 0 | 0 | 0 |
| Size of granulomas | ||||
| Macrogranulomas (equal to diameter of 2–4 intact crypts) | 19/19 (100) | 0 | NA | NA |
| Microgranulomas (equal to diameter of <1 intact crypt) | 3/19 (15.7) | 8/8 (100) | NA | NA |
| Site of granulomas | ||||
| Mucosal | 3/19 (15.7) | 8/8 (100) | NA | NA |
| Submucosal | 19/19 (100) | 0 | NA | NA |
| Therapeutic ATT given (post biopsy) | ||||
| No | 0 | 5 (62.5) | 0 | 24 (57.1) |
| Yes | 19 (100) | 3 (37.5) | 10 (100) | 18 (42.8) |
| Duration of treatment (mo) | 7.7±2.0 | 2.0±2.8 | 9.6±5.2 | 4.9±5.5 |
| History of steroid intake (post biopsy) | ||||
| No | 19 (100) | 3 (37.5) | 6 (60.0) | 20 (47.6) |
| Yes | 0 | 5 (62.5) | 0 | 18 (42.8) |
| Not known | 0 | 0 | 4 (40.0) | 4 (9.5) |
Values are presented as mean±SD or number (%).
iTB, intestinal tuberculosis; NA, not applicable; ATT, antitubercular treatment.