Table 13.

Summary of absolute organ weights for 90-day study on curcumin.

Group		Absolute Organ Weights (g)
n=20   mg/kg   bw/d		Adrenal glands	Heart	Brain	Liver	Kidneys	Spleen	Testes/Ovaries	Epididymides/Uterus
Males
Vehicle	Mean	0.056	1.028	2.104	10.577	2.293	0.665	3.661	1.451
0	SD	0.007	0.070	0.119	1.290	0.252	0.082	0.366	0.141
250	Mean	0.059	1.028	2.174	10.378	2.332	0.614	3.776	1.497
	SD	0.007	0.080	0.090	1.118	0.247	0.104	0.218	0.103
500	Mean	0.062	1.101∗+	2.222∗+	11.452	2.605∗∗+	0.723	3.898∗+	1.546∗+
	SD	0.007	0.097	0.124	0.874	0.578	0.140	0.492	0.134
1000	Mean	0.056	1.049	2.126	11.217	2.398	0.665	3.736	1.516
	SD	0.011	0.079	0.161	1.263	0.176	0.106	0.416	0.117
Ref Item	Mean	0.060	1.005	2.110	10.904	2.334	0.608∗-	3.755	1.498
1000	SD	0.010	0.082	0.132	1.064	0.186	0.137	0.257	0.103
Females
Vehicle	Mean	0.071	0.751	2.044	6.662	1.805	0.445	0.171	0.696
0	SD	0.008	0.066	0.068	0.705	1.186	0.049	0.032	0.177
250	Mean	0.072	0.668	2.010	6.536	1.506	0.500	0.163	0.593
	SD	0.009	0.207	0.121	0.591	0.103	0.098	0.015	0.101
500	Mean	0.070	0.729	2.036	6.263∗-	1.498	0.457	0.173	0.625
	SD	0.012	0.079	0.119	0.664	0.152	0.065	0.022	0.109
1000	Mean	0.077∗+	0.779	2.091	7.074	1.607	0.474	0.179	0.637
	SD	0.011	0.054	0.116	0.681	0.154	0.056	0.031	0.159
Ref Item	Mean	0.078	0.764	2.066	7.023	1.541	0.481	0.178	0.710
1000	SD	0.016	0.076	0.132	0.950	0.173	0.077	0.038	0.223

N= number of animals;  ^∗+/∗-= statistically significant increase/decrease as compared to vehicle control (p<0.05);  ^{∗∗+/∗∗-}= statistically significant increase/decrease as compared to vehicle control (p<0.01); Ref, reference.