. 2018 Jul 15;2018:7287820. doi: 10.1155/2018/7287820

Table 2.

GFAP level in the cerebral cortex, cerebellum, and brainstem of control and KA-induced groups at multiple time points.

	Subgroups	GFAP level (ng/g wet tissue)				Kruskal-Wallis H test/ANOVA test
		(n = 6 per group for each time point)				Kruskal-Wallis H test/ANOVA test
		CONTROL	KA	TH + KA	TPM + KA	p value
Cerebral Cortex Median (IqR)	2 h	6.15 (3.57)	17.88 (15.89)^a	11.40 (2.26)^a	10.98 (3.03)^a	0.001
	24 h	5.61 (6.57)	14.17 (15.43)^a	11.14 (5.23)	11.24 (5.49)	0.019
	48 h	4.45 (5.51)	11.71 (13.32)	8.96 (7.73)	8.44 (10.50)	0.056

Cerebellum Median (IqR)	2 h	3.66 (1.24)	8.85 (5.05)^a	4.95 (2.01)^b	5.73 (1.82)^a	0.001
	24 h	3.74 (1.78)	10.76 (5.99)^a	4.57 (0.98)	4.95 (3.57)	0.006
	48 h	2.98 (0.46)	7.03 (5.96)^a	3.80 (1.30)^b	5.21 (1.96)^a	0.001

Brainstem Mean ± SEM	2 h	10.19 ± 1.98	21.28 ± 1.90^a	14.13 ± 1.36	15.71 ± 2.31	0.005
	24 h	9.71 ± 1.14	22.06 ± 3.65^a	14.11 ± 2.71	15.20 ± 1.87	0.020
	48 h	9.12 ± 0.95	16.86 ± 1.55^a	12.59 ± 1.42	12.30 ± 1.37	0.006

For the cerebral cortex and cerebellum, descriptive data are presented as the median (IqR) (n = 6 rats per group for each time point) and the significant difference was determined by nonparametric test, Kruskal-Wallis test, followed by Mann–Whitney U (MW) post hoc test with p<0.05 indicating significant difference. ^ap < 0.05 versus control group (MW); ^bp < 0.05 versus KA group (MW). For the brainstem, descriptive data are presented as the mean ± SEM (n = 6 rats per group for each time point) and the significant difference was determined by parametric test, ANOVA test, followed by Tukey post hoc test with p<0.05 indicating significant difference. ^ap < 0.05 versus control group; ^bp < 0.05 versus KA group. ANOVA, one-way analysis of variance; GFAP, glial fibrillary acidic protein; IqR; interquartile range; KA, kainic acid; TH, tualang honey; TPM, topiramate; SEM, the standard error of the mean.