Table 3.
95% confidence interval (lower and upper mean) of the pharmacokinetic parameters of silybin after the oral administration of silymarin SMEDDS soft capsules.
| Parameters | 95% Confidence Interval (lower and upper mean) |
|---|---|
| Cmax (ng/mL) | 536.63–1088.23 |
| AUC0-t (ng.h/mL) | 489.64–827.96 |
| AUC0-inf (ng.h/mL) | 506.49–847.48 |
Cmax: maximum observed plasma concentration; AUC0-t: area under the plasma concentration versus time curve up to the last; AUC0-inf: area under the plasma concentration versus time curve with the concentration extrapolated based on the elimination rate constant.