(a) Tumor stage

Pathologic features	Variables	T1		T2		T3		T4		Total		Chi- square Test
		Number	%	Number	%	Number	%	Number	%	Number	%	p
S100A4 expression	Absent	1	100	4	36.4	3	18.6	8	6.7	16	10.8	0.001
	Present	0	0	7	63.6	13	81.3	112	93.3	132	89.2
	Total	1	100	11	10	16	100	120	100	148	100
Distribution Of Tumor Tissue Staining	Absent	1	100	4	36.4	3	18.8	8	6.7	16	10.8	0.007
	Superficial	0	0	4	36.4	4	25	32	26.7	40	27
	Deep	0	0	0	0	3	18.8	12	10	15	10.1
	Complete	0	0	3	27.3	6	37.5	68	56.7	77	52
	Total	1	100	11	100	16	100	120	100	148	100