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. 2018 Jul 12;2018:5423961. doi: 10.1155/2018/5423961

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Copyright © 2018 Ling-Yong Xiao et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Acupuncture rescues long-term-potentiation deficits induced by 2VO. Sham: sham-operated group, 2VO + Acu: 2VO + acupuncture group, 2VO + Pla-acu: 2VO + placebo-acupuncture group. (a) 2VO (colorless circles) decreased long-term-potentiation (LTP) induced by high frequency stimulation (HFS, arrow) in the perforant path-dentate gyrus (PP-DG) area versus those of Sham rats (black circles). (b) Acupuncture (red circles) increased PP-DG LTP induced by HFS versus those of 2VO rats. (c) Placebo-acupuncture (gray circles) did not enhance LTP of VD rats. (d) The histogram showing the level of LTP during 60 min after HFS. (n = 6 rats for each group.) (∗∗: P<0.05,∗∗∗: P<0.001, compared as indicated.) Inset traces are sample traces recorded before (black) and after (red) HFS. Horizontal bar: 5 ms; vertical bar: 5 mV.