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Homology-based models of the LolA–LolCDE complex. Models of full-length LolCDE generated from the nucleotide-free and ATP-bound structures of MacB (5NIL and 5LIL, respectively). LolA has been docked according to LolA–LolC crystallographic data (6F3Z). Positions at which mutations confer resistance to both compound 2 (21) and G0507 (19) inhibitors are shown mapped to the ATP-bound state.
