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Targeting PAR2 in endosomes of nociceptors. Representative images (of three experiments) of trafficking of Cy5 tripartite probes and mPAR2-GFP to the soma (A) and neurites (B) of mouse DRG neurons. The scale bar (5 µm) in the bright-field image applies to all panels in the same row, except for Inset, which is a magnification of the dashed box in the merged panels. Arrows show proximity of vesicles containing mPAR2-GFP and Cy5-Chol.
