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. 2018 Jul 27;12:222. doi: 10.3389/fncel.2018.00222

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Copyright © 2018 Wang, Chen, Zhou, Xu, Qian, Ni and Qian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Mild ER stress ameliorated LPS-induced cognitive impairment in the hippocampus. (A) Contextual fear response, as measured by freezing time, was determined in the rats (n = 12). (B) The number of learning trials was recorded to analyze the Y-maze test (n = 12). The data are presented as the mean ± SEM. ^∗P < 0.05, ^∗∗P < 0.01 vs. naïve group. ^#P < 0.05, ^##P < 0.01 vs. LPS treatment group. ^∧P < 0.05, ^∧∧P < 0.01 vs. TM treatment group. The data are representative of three independent experiments.