Table IV. LOD and LOQ of anti-CSP mAbs interactions with CSP Ags.

Ag	Ab/Diluent	Specific Binding of Diluent Alone, Mean ± SD (nm), n = 12	LLOD (nM)		LLOQ (nM)		Upper LOD/LOQ (nM)
			Calculated	Observed	Calculated	Observed
PF16	AB000236
	In PBS	0.0010 ± 0.0033	2.0	2.3	3.9	3.3	50.0
	In NHS	0.0035 ± 0.0100	0.3	0.5	1.1	3.3	25.0
NANP6	AB000334
	In PBS	−0.0045 ± 0.0019	0.8	0.7	1.6	1.3	100.0
	In NHS	−0.0440 ± 0.0158	0.6	0.3	1.0	3.3	50.0
CSP-FL	AB000236
	In PBS	0.0001 ± 0.0025	0.5	0.4	0.9	1.1	25.0
	In NHS	−0.0261 ± 0.0049	0.007	0.4	0.04	3.3	13.3
	AB000334
	In PBS	0.0020 ± 0.0034	0.4	0.4	1.2	1.7	100.0
	In NHS	−0.0256 ± 0.0059	0.2	0.4	0.4	3.3	50.0