Table 3.
HRQoL among 1955 individuals with MS in 2013, presented by disability levels.
|
MS patients with EQ-5D responses, by level of disability measured by EDSS |
All MS patients with EQ-5D responses | ||||
|---|---|---|---|---|---|
| 0–3.5 | 4–5.5 | 6–6.5 | 7–9.5 | ||
| Health dimensions | Median (Q1–Q3) n=1323 | Median (Q1–Q3) n=191 | Median (Q1–Q3) n=122 | Median (Q1–Q3) n=48 | Median (Q1–Q3) n=1684 |
| Mobility | 1 (1–1) | 2 (2–2) | 2 (2–2) | 2 (2–3) | 1 (1–2) |
| Self-care | 1 (1–1) | 1 (1–1) | 1 (1–2) | 2 (1–3) | 1 (1–1) |
| Usual activities | 1 (1–2) | 2 (1–2) | 2 (1–2) | 2 (2–3) | 1 (1–2) |
| Pain/discomfort | 2 (1–2) | 2 (2–2) | 2 (2–2) | 2 (2–3) | 2 (1–2) |
| Anxiety/depression | 1 (1–2) | 2 (1–2) | 2 (1–2) | 2 (1–2) | 1 (1–2) |
| Swedish experience-based index values, mean (95% CI) | 0.867 (0.860–0.873) | 0.752 (0.735–0.768) | 0.724 (0.704–0.745) | 0.626 (0.584–0.668) | 0.836 (0.830–0.842) |
| UK general population-based index values, mean (95% CI) | 0.766 (0.753–0.778) | 0.579 (0.541–0.616) | 0.526 (0.476–0.576) | 0.141 (0.019–0.264) | 0.709 (0.697–0.722) |
| EQ-VAS scale | 71 (70–73) | 57 (54–60) | 54 (49–58) | 45 (38–52) | 68 (67–69) |
Any non-overlapping 95% CIs, between EDSS categories, are indicated in the table: higher 95% CIs as bold text and lower 95% CIs as italics.
EDSS: Expanded Disability Status Scale; EQ-5D: EuroQol Group’s five-dimension health state questionnaire with three levels of severity; HRQoL: health-related quality of life; MS: multiple sclerosis; Q1–Q3: interquartile range, 1st to 3rd quartile.