Table 3.
Frequency of blood cell types by flow cytometry.
| Parameter | Male Mfap2Prx−/− | Female Mfap2Prx−/− | Mfap2−/− | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
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| Genotype | Mean | p value | Genotype | Mean | p value | Genotype | Mean | p value | |
| Blood count Ab# | WT | 7.96 ± 0.63E+06 | 0.314 | WT | 7.65 ± 0.71E+06 | 0.925 | WT | 3.43 ± 0.84E+05 | 0.020 |
| Cre+ | 8.91 ± 0.67E+06 | Cre+ | 7.78 ± 0.50E+06 | Mfap2−/− | 1.21 ± 0.33E+06 | ||||
| Neutrophil | WT | 14.31 ± 1.02 | 0.404 | WT | 15.63 ± 0.96 | 0.633 | WT | 9.24 ± 1.16 | 0.004 |
| Cre+ | 13.12 ± 0.94 | Cre+ | 16.85 ± 3.55 | Mfap2−/− | 4.60 ± 0.83 | ||||
| Eosinophil | WT | 1.84 ± 0.38 | 0.571 | WT | 2.55 ± 0.30 | 0.476 | WT | – | – |
| Cre+ | 1.51 ± 0.46 | Cre+ | 2.05 ± 0.77 | Mfap2−/− | – | ||||
| Monocyte | WT | 5.13 ± 0.70 | 0.475 | WT | 5.44 ± 0.69 | 0.672 | WT | 2.20 ± 0.37 | 0.026 |
| Cre+ | 4.47 ± 0.53 | Cre+ | 6.08 ± 1.41 | Mfap2−/− | 1.23 ± 0.14 | ||||
| Ly6C+ Monocyte | WT | 2.53 ± 0.42 | 0.790 | WT | 3.18 ± 0.51 | 0.914 | WT | 1.35 ± 0.28 | 0.037 |
| Cre+ | 2.38 ± 0.34 | Cre+ | 3.29 ± 0.64 | Mfap2−/− | 0.46 ± 0.02 | ||||
| Lyc6− Monocyte | WT | 2.48 ± 0.33 | 0.238 | WT | 2.24 ± 0.23 | 0.396 | WT | 0.85 ± 0.16 | 0.398 |
| Cre+ | 1.97 ± 0.23 | Cre+ | 2.74 ± 0.75 | Mfap2−/− | 0.68 ± 0.02 | ||||
| B Cell | WT | 48.72 ± 1.64 | 0.616 | WT | 37.13 ± 2.69 | 0.476 | WT | 55.75 ± 2.09 | 0.058 |
| Cre+ | 50.2 ± 2.53 | Cre+ | 41.75 ± 7.55 | Mfap2−/− | 62.425 ± 1.90 | ||||
| T Cell | WT | 17.62 ± 0.91 | 0.68 | WT | 25.48 ± 1.65 | 0.242 | WT | 25.9 ± 2.51 | 0.269 |
| Cre+ | 18.4 ± 1.72 | Cre+ | 21.55 ± 0.75 | Mfap2−/− | 21.98 ± 1.29 | ||||
| CD8 T Cell | WT | 8.30 ± 0.51 | 0.559 | WT | 13.03 ± 0.82 | 0.083 | WT | 11.70 ± 0.84 | 0.636 |
| Cre+ | 8.87 ± 0.88 | Cre+ | 9.94 ± 0.01 | Mfap2−/− | 11.12 ± 0.67 | ||||
| CD4 T Cell | WT | 8.69 ± 0.54 | 0.831 | WT | 11.34 ± 1.38 | 0.874 | WT | 13.14 ± 1.98 | 0.279 |
| Cre+ | 8.91 ± 0.96 | Cre+ | 10.91 ± 1.19 | Mfap2−/− | 10.20 ± 0.73 | ||||