Table 1.
Association of CL-L1 expression with clinicopathological features in HCCs
| Clinical features | Cases | Colec10 expression
|
P-value | |
|---|---|---|---|---|
| Low level (%) | High level (%) | |||
| Age (years) | 0.113 | |||
| <50 | 56 | 38 (67.9) | 18 (32.1) | |
| ≥50 | 80 | 43 (53.8) | 37 (46.2) | |
| Gender | 0.440 | |||
| Male | 129 | 78 (60.5) | 51 (39.5) | |
| Female | 7 | 3 (42.9) | 4 (57.1) | |
| HBsAg | 0.572 | |||
| Negative | 17 | 9 (52.9) | 8 (47.1) | |
| Positive | 119 | 71 (59.7) | 48 (40.3) | |
| AFP (ng/mL) | 0.098 | |||
| ≤25 | 47 | 23 (48.9) | 24 (51.1) | |
| >25 | 89 | 58 (65.2) | 31 (34.8) | |
| Cirrhosis | 0.367 | |||
| No | 24 | 12 (50.0) | 12 (50.0) | |
| Yes | 112 | 68 (60.7) | 44 (39.3) | |
| Tumor number | 0.676 | |||
| Solitary | 106 | 61 (57.5) | 45 (42.5) | |
| Multiple | 30 | 19 (63.3) | 11 (36.7) | |
| Tumor encapsulation | 0.343 | |||
| Complete | 95 | 53 (55.8) | 42 (44.2) | |
| None | 41 | 27 (65.9) | 14 (34.1) | |
| Vascular invasion | 0.013 | |||
| Absent | 115 | 62 (53.9) | 53 (46.1) | |
| Present | 19 | 16 (84.2) | 3 (15.8) | |
| Surrounding invasion | 0.003 | |||
| Absent | 106 | 55 (51.9) | 51 (48.1) | |
| Present | 30 | 25 (83.3) | 5 (16.7) | |
| Clinical stage | 0.598 | |||
| I–II | 81 | 46 (56.8) | 35 (43.2) | |
| III–IV | 55 | 34 (61.8) | 21 (38.2) | |
Note: Statistical significance (P<0.05) is shown in bold.
Abbreviations: AFP, alpha-fetoprotein; Colec10, collectin subfamily member 10; HBsAg, hepatitis B surface antigen; HCC, hepatocellular carcinoma.