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. 2018 Aug 1;11:159–171. doi: 10.2147/JAA.S151849

Figure 3.

Figure 3

Increases in lung lavage content of inflammatory cells and protein after HDM exposure are normalized by the addition of GC021109.

Notes: (A) Total inflammatory cell numbers in lung lavage fluid from mice after exposure to saline (solid green), HDM (green striped), GC021109 (10 µg/kg weight/dose – solid red, 100 µg/kg weight/dose – solid black), and HDM + GC021109 (10 µg/kg weight/dose – striped red, 100 µg/kg weight/dose – striped black). Counts were performed using a hemocytometer. (B) Cumulative differential cell counts in lung lavage from saline-treated, HDM-treated, and HDM + GC021109 (100 µg/kg weight/dose)-treated mice. (C) Protein concentration in lung lavage fluid. Conditions were the same as in (A). Data represent mean ± SEM; N=5 mice per group. *P<0.01, compared to control; ^P<0.01, compared to HDM; ‡P<0.001, compared to HDM.

Abbreviations: HDM, house dust mite; LL, lung lavage; SEM, standard error of means.