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. 2018 Aug 1;10:2389–2400. doi: 10.2147/CMAR.S162887

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© 2018 Xiao et al. This work is published and licensed by Dove Medical Press Limited

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LRH-1 was frequently upregulated in HCC clinical specimens.

Notes: (A) LRH-1 immunohistochemistry. Three representative micrographs of LRH-1-immunostained tissue microarray spots of HCC and adjacent tissues. Magnification, ×400; bars, 30 µm. The cells in tumor-adjacent tissues showed detectable or weak nuclear immunoreactivity. Intense nuclear immunosignals were detected in cancer cells in HCC tissues. (B) LRH-1 IRS analysis performed on HCC and adjacent tissues. Results showed that HCC tissues showed significantly higher LRH-1 expression than tumor-adjacent tissues. P<0.001 vs tumor-adjacent tissues.

Abbreviations: HCC, hepatocellular carcinoma; IRS, immunoreactivity score.