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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Environ Toxicol Pharmacol. 2018 Feb 3;58:196–201. doi: 10.1016/j.etap.2018.01.010

Fig. 3.

Fig. 3

Inhibition of SULT2A1-catalyzed sulfation of 1.0 μM DHEA by PCB metabolites. (a) Inhibition of SULT2A1 by 4’-OH PCB 3, 4-OH-PCB 8, 4-OH-PCB 11, 4’-OH-PCB 25 and 4-OH-PCB 52. Control rates for sulfation of DHEA were 63.8, 69.6, 69.1, 74.6, and 84.4 (nmol/min/mg), respectively. (b) Inhibition of SULT2A1 by 4’-PCB 3 sulfate, 4-PCB 8 sulfate, 4-PCB 11 sulfate, 4’-PCB 25 sulfate and 4-PCB 52 sulfate. Control rates for sulfation of DHEA were 63.1, 44.6, 55.2, 89.4, and 40.8 (nmol/min/mg), respectively.