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. 2018 Aug 1;11:4479–4490. doi: 10.2147/OTT.S164670

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© 2018 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Cordycepin induces apoptosis in pancreatic cancer cells.

Notes: (A, B) MIAPaCa-2 and Capan-1 cells were incubated with cordycepin (0, 100, 200, and 400 μg/mL) for 48 h, then stained with Annexin V/PI and analyzed by flow cytometry. The Q3 quadrant (Annexin V−/PI−), Q4 quadrant (Annexin V+/PI−), and Q2 quadrant (Annexin V+/PI+) represent the group of normal cells, early apoptotic cells, and late apoptotic cells, respectively. (C, D) The percentage of cells in each stage is presented. Data are presented as mean ± SD (n=3). *p<0.05, **p<0.01, ***p<0.001.