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. 2018 Aug 1;11:4479–4490. doi: 10.2147/OTT.S164670

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© 2018 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Cordycepin-induced apoptosis via regulation of caspase and Bcl-2 family members in pancreatic cancer cells.

Notes: (A, B) Representative results of Western blot analysis for the protein level of cleaved caspase-3, cleaved caspase-9, cleaved PARP, Bcl-2, and Bax in MIAPaCa-2 and Capan-1 cells treated with cordycepin at indicated doses for 48 h. β-actin was used as a loading control. Band density of Bcl-2 and Bax are presented. (C, D) Ratio of Bcl-2 to Bax determined by band density compared with the control (designated as 1.00). Data are presented as mean ± SD (n=3). *p<0.05, **p<0.01, ***p<0.001.