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. 2018 Aug 1;11:4479–4490. doi: 10.2147/OTT.S164670

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© 2018 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Cordycepin induces S-phase arrest.

Notes: (A, B) MIAPaCa-2 and Capan-1 cells were treated with cordycepin (0, 100, 200, 400 μg/mL) for 48 h and the DNA content was analyzed by flow cytometry. (C, D) The percentage of cells in the G1, S, and G2/M phases of the cell cycle are shown. Results are expressed as mean ± SD from 3 independent experiments. (E, F) Representative results of Western blot analysis for the protein level of cyclin A and Cdk-2 treated with cordycepin at indicated doses for 48 h. GAPDH was used as a loading control.