Table 2.
Mixed-muscle protein and muscle mitochondrial protein d9-leucine enrichment
Biopsy time
|
|||
---|---|---|---|
120 min | 300 min | 540 min | |
Mixed-muscle protein (MPE) | |||
Lean subjects | 0.007 ± 0.001 | 0.017 ± 0.001# | 0.034 ± 0.002& |
Subjects with obesity | 0.006 ± 0.001 | 0.014 ± 0.001# | 0.034 ± 0.004& |
Mitochondrial protein (MPE) | |||
Lean subjects | 0.011 ± 0.001 | 0.023 ± 0.001# | 0.045 ± 0.004& |
Subjects with obesity | 0.010 ± 0.001 | 0.019 ± 0.001# | 0.042 ± 0.002& |
Values represent the mean ± SEM. Biopsy time reflects the time after the start of leucine tracer infusion (see text); 120 and 300 min correspond to fasted-state plasma amino acid concentrations, whereas 540 min corresponds to elevated plasma amino acid concentrations; MPE, molar percent excess. There were significant time (P ≤ 0.05) but not group (P > 0.05) main effects for both mixed-muscle and mitochondrial proteins.
P ≤ 0.05 versus 120 min;
P ≤ 0.05 versus both 120 and 300 min.