Table 4.
Patient Characteristics According to Concordant or Discordant LSM and ELFScores
|
Low LSM Low ELF n = 137 |
Low LSM High ELF n = 21 |
High LSM Low ELF n = 33 |
High LSM High ELF n = 39 |
P Value | |
|---|---|---|---|---|---|
| Age* (years) | 55.0 ± 12.3 | 66.0 ± 8.0 | 50.9 ± 13.2 | 62.6 ± 8.1 | <0.001 |
| Male sex,† n (%) | 74 (54.0) | 11 (52.4) | 19 (57.6) | 22 (56.4) | 0.973 |
| Caucasian ethnicity,† n (%) | 104 (75.9) | 13 (61.9) | 27 (81.8) | 33 (84.6) | 0.213 |
| BMI‡ (kg/m2) | 31.3 (28.2‐35.6) | 30.5 (27.1‐37.3) | 40.5 (34.6‐45.3) | 36.3 (31.6‐42.2) | <0.001 |
| Waist circumference* (cm) | 110.1 ± 14.6 | 107.3 ± 19.3 | 132.2 ± 15.9 | 124.0 ± 17.8 | <0.001 |
| T2DM,§ n (%) | 104 (75.9) | 16 (76.2) | 29 (87.9) | 38 (97.4) | 0.006 |
| Metabolic syndrome,§ n (%) | 107 (78.1) | 17 (81.0) | 30 (90.9) | 38 (97.4) | 0.011 |
| eGFR‡ (mL/minute) | 90 (78‐90) | 81 (63‐90) | 90 (86‐90) | 80 (65‐90) | 0.003 |
| ALT‡ (IU/mL) | 30 (21‐51) | 22 (18‐34) | 46 (31‐61) | 38 (33‐66) | <0.001 |
| AST‡ (IU/mL) | 21 (16‐30) | 24 (15‐29) | 30 (16‐37) | 40 (27‐66) | <0.001 |
| GGT‡ (IU/mL) | 26 (20‐44) | 33 (17‐65) | 50 (23‐79) | 72 (47‐128) | <0.001 |
| Platelet count‡ (× 109) | 247 (208‐293) | 245 (216‐303) | 243 (210‐291) | 209 (162‐263) | 0.019 |
| Albumin‡ (g/L) | 42 (40‐44) | 41 (40‐42) | 40 (38‐43) | 41 (39‐43) | 0.066 |
| HbA1c‡ (%) | 7.3 (5.9‐8.6) | 6.7 (5.8‐7.7) | 7.7 (6.8‐9.0) | 7.7 (6.7‐9.1) | 0.029 |
Data only presented for the 230 patients for whom a valid LSM reading was calculated. *Continuous data (mean ± SD) analyzed using a one‐way analysis of variance; †categorical data analyzed using Pearson's chi‐squared test; ‡continuous data (median [IQR]) analyzed using the Kruskal‐Wallis test; §categorical data analyzed using Fisher's exact test.
Abbreviations: eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c.