Table 1. Serum parameters of RD-rats and HFD-rats supplemented with or without ENC® for 21 days.
RD | RD+ ENC®a | HFD | HFD+ ENC®a | |
---|---|---|---|---|
Day | 0–21 | 21 | 0–21 | 21 |
ASTb | 242 ± 60 | 236 ± 70 | 237 ± 60 | 238 ± 60 |
ALTc | 67 ± 23 | 64 ± 25 | 60 ± 23 | 60 ± 21 |
Cholesterold | 3.16 ± 0.23 | 3.10 ± 0.19 | 3.68 ± 0.17** | 3.28 ± 0.16° |
LDL Cholesterold | 0.90 ± 0.03 | 0.88 ± 0.09 | 1.02 ± 0.02* | 0.92 ± 0.07° |
HDL Cholesterold | 2.34 ± 0.08 | 2.36 ± 0.03 | 2.18 ± 0.04* | 2.26 ± 0.03° |
Triglycerided | 1.24 ± 0.14 | 1.22 ± 0.16 | 2.03 ± 0.10** | 1.46 ± 0.07°° |
a) ENC® 20 mg/kg/day.
b) AST, Aspartate transaminases (Units/ml).
c) ALT, Alanine transaminases (Units/ml).
d) Expressed as mmol/l.
To improve clarity, since values between RD 0 day and RD 21 days did not change significantly, they have been pooled; the same was for HFD 0 day and HFD 21 days. Results are reported as mean ± S.D. (n = 10/group) and analyzed by using ANOVA followed by Bonferroni post test.
*P < 0.05
**P < 0.01, vs RD-rats, same time.
°P < 0.05
°°P < 0.01 vs HFD 0–21.