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. 2018 Aug 6;13(8):e0201540. doi: 10.1371/journal.pone.0201540

Table 1. Serum parameters of RD-rats and HFD-rats supplemented with or without ENC® for 21 days.

RD RD+ ENC®a HFD HFD+ ENC®a
Day 0–21 21 0–21 21
ASTb 242 ± 60 236 ± 70 237 ± 60 238 ± 60
ALTc 67 ± 23 64 ± 25 60 ± 23 60 ± 21
Cholesterold 3.16 ± 0.23 3.10 ± 0.19 3.68 ± 0.17** 3.28 ± 0.16°
LDL Cholesterold 0.90 ± 0.03 0.88 ± 0.09 1.02 ± 0.02* 0.92 ± 0.07°
HDL Cholesterold 2.34 ± 0.08 2.36 ± 0.03 2.18 ± 0.04* 2.26 ± 0.03°
Triglycerided 1.24 ± 0.14 1.22 ± 0.16 2.03 ± 0.10** 1.46 ± 0.07°°

a) ENC® 20 mg/kg/day.

b) AST, Aspartate transaminases (Units/ml).

c) ALT, Alanine transaminases (Units/ml).

d) Expressed as mmol/l.

To improve clarity, since values between RD 0 day and RD 21 days did not change significantly, they have been pooled; the same was for HFD 0 day and HFD 21 days. Results are reported as mean ± S.D. (n = 10/group) and analyzed by using ANOVA followed by Bonferroni post test.

*P < 0.05

**P < 0.01, vs RD-rats, same time.

°P < 0.05

°°P < 0.01 vs HFD 0–21.