Table 1. Amygdala-nucleus accumbens associations.
Metabolite | Functional Connectivity | r | p | q | df |
Indole | B_R_NAcc | 0.59608 | < 0.001 | < 0.001 | 62 |
IAA | S_R_Amg | 0.37640 | 0.003 | 0.011 | 62 |
Indole | S_R_NAcc | 0.36637 | 0.004 | 0.011 | 62 |
IAA | S_R_NAcc | 0.33201 | 0.009 | 0.018 | 62 |
Skatole | S_R_NAcc | 0.31022 | 0.015 | 0.022 | 62 |
Skatole | S_L_NAcc | 0.33839 | 0.008 | 0.046 | 62 |
Clinical/Behavioral Measure | Functional Connectivity | r | p | q | df |
YFAS | S_L_NAcc | 0.59632 | < 0.001 | < 0.001 | 41 |
ANX | S_L_NAcc | 0.29999 | 0.019 | 0.056 | 62 |
YFAS | S_R_NAcc | 0.36944 | 0.019 | 0.114 | 62 |
Metabolite | Anatomical Connectivity | r | p | q | df |
Skatole | S_L_Amg | 0.55362 | < 0.001 | < 0.001 | 61 |
Metabolite | Clinical/Behavioral Measure | r | p | q | df |
Skatole | YFAS | 0.48043 | 0.002 | 0.017 | 41 |
Indole | ANX | -0.28741 | 0.025 | 0.086 | 62 |
Indole | BMI | 0.28036 | 0.029 | 0.090 | 62 |
This table shows all significant associations prior to FDR correction with r, p, FDR-corrected q values, and df (degrees of freedom) for the amygdala-nucleus accumbens circuit.
Abbreviations: ANX, Hospital anxiety and depression (HAD) scale anxiety score; B_R_NAcc, Betweenness centrality of the right nucleus accumbens; BMI, Body mass index; IAA, Indoleacetic acid; S_L_Amg, Degree strength of the left amygdala; S_L_NAcc, Degree strength of the left nucleus accumbens; S_R_Amg, Degree strength of the right amygdala; S_R_NAcc, Degree strength of the right nucleus accumbens; YFAS, Yale food addiction scale score.