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Multivariate analysis of SMAD4 expression adjusted for other patient characteristics in patients with recurrent HNSCC.
| Overall Survival | |||
|---|---|---|---|
| Characteristic | HR | 95% CI | P value |
| SMAD4 | |||
| Negative vs. positive | 3.05 | [1.34, 6.95] | 0.008 |
| M stage | |||
| M1 vs. M0 | 5.85 | [1.83, 18.67] | 0.003 |
| Primary tumor site | |||
| Oropharynx vs. other | 4.07 | [1.65, 10.06] | 0.002 |
| Age | 1.008 | [0.98, 1.04] | 0.64 |
