Table 2.
Effect of oxytocin (OT) treatment on the levels of reduced glutathione (GSH), thiobarbituric acid-reactive substances (TBARS) and nitrite (NO2) in cisplatin (CP)- induced nephrotoxicity.
| GSH (μmol/g protein) | TBARS (n mol/g protein) | NO2 (μmol/mg protein) | |
|---|---|---|---|
|
| |||
| Control | 1.80 (0.53) | 20.6 (3.30) | 0.10 (0.14) |
| OT | 1.43 (0.29) | 23.2 (5.70) | 0.11 (0.17) |
| CP | 0.20 (0.10)a | 51.3 (5.11)a | 0.38 (2.20)a |
| OT+CP | 1.20 (0.41)b | 25.8 (4.93)b | 0.18 (0.20)b |
Data are the mean (SD) of 12 rats in each group. OT: oxytocin; CP: cisplatin.
a
P<.05 vs. control group
b
P<.05 vs. CP group.