Figure 1.

Regional plots of association for the Asian-specific and trans-ethnic meta-analyses at the three known HSCR-associated loci. Significance of association is reported in P-values for the fixed-effects Asian-specific meta-analysis (upper panel) and in Bayes factors for the trans-ethnic meta-analyses (lower panel). Genomic regions covered by the 99% credible set are highlighted by the purple boxes. The lead SNP of each locus is highlighted by purple diamond. Color indicates the LD (r²) with the lead SNP.