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. Author manuscript; available in PMC: 2019 Aug 6.
Published in final edited form as: Mol Pharm. 2018 Jun 25;15(8):3434–3441. doi: 10.1021/acs.molpharmaceut.8b00424

Figure 1.

Figure 1

Representative images of the hindlimb ischemia model generation, showing the step-by-step process of the surgical procedure that includes the isolation of the femoral artery, its ligation at the proximal and distal sites followed by its complete excision. Laser Doppler images acquired before and after the induction of ischemia corroborates the reduced blood flow in the operated leg.