Figure 5.

Ex vivo⁶⁴ Cu-NOTA-YY146 biodistribution data obtained right after the last PET scan (48h p.i.) at A) postoperative day 17 and B) postoperative day 10. In blocking studies, mice were administered a blocking dose (10 mg/kg) of cold YY146 24 hours before the radiolabeled tracer was intravenously injected. Animals were sacrificed, and tissue samples were harvested, wet-weighed, gamma counted, and tracer uptake in the different tissues was calculated as %ID/g (mean ± SD).