Table 4.
The impact of clinical features on the rate of ticagrelor metabolism according to the additional multiple regression analysis.
| Parameter | Regression coefficient | Standard error | 95% confidence interval | p value | R2 (overall significance) |
|---|---|---|---|---|---|
| Constant | 17.1 | 7.2 | 2.8; 31.4 | 0.02 | 0.21 (0.00014) |
| Age | 0.1 | 0.1 | −0.1; 0.3 | 0.36 | |
| Gender | 1.6 | 2.0 | −2.3; 5.4 | 0.43 | |
| STEMI | −8.2 | 2.1 | −12.4; −4.0 | 0.0002 | |
| Morphine co-administration | −2.2 | 2.2 | −6.6; 2.1 | 0.31 | |
| Current smoker | 4.2 | 2.0 | 0.2; 8.3 | 0.04 | |
| Diabetes mellitus | −5.9 | 2.2 | −10.3; −1.6 | 0.008 |
STEMI: ST-elevation myocardial infarction.