Table 1.
Baseline characteristics of the study population.
| Characteristic | Patients (n = 162) | Controls (n = 108) | p value |
|---|---|---|---|
| Age (years) | 71.7 ± 8.8 | 71.4 ± 9.5 | 0.816 |
| Male (%) | 105 (64.8) | 70 (64.8) | 1.000 |
| SBP (mmHg) | 152.9 ± 23.7 | 138.7 ± 19.3 | <0.001 |
| DBP (mmHg) | 77.7 ± 12.8 | 78.8 ± 8.5 | 0.407 |
| BMI (kg/m2) | 23.1 ± 3.3 | 23.5 ± 3.6 | 0.371 |
| FBG (mmol/L) | 5.30 (4.76, 6.07) | 5.05 (4.56, 5.74) | 0.016 |
| TG (mmol/L) | 1.34 (1.00, 1.71) | 1.41 (1.06, 1.97) | 0.082 |
| TC (mmol/L) | 4.42 (3.84, 5.17) | 4.35 (3.63, 5.25) | 0.401 |
| HDL-C (mmol/L) | 1.18 ± 0.22 | 1.18 ± 0.23 | 0.946 |
| LDL-C (mmol/L) | 2.54 (2.13, 3.26) | 2.69 (1.99, 3.36) | 0.506 |
| HbA1C (%) | 5.9 (5.5, 6.3) | 5.7 (5.4, 6.2) | 0.079 |
| Homocysteine (μmol/L) | 13.0 (11.0, 17.2) | 11.8 (9.4, 14.8) | 0.006 |
| Serum creatinine (μmol/L) | 70.5 ± 17.2 | 70.0 ± 16.2 | 0.829 |
| Fibrinogen (g/L) | 3.62 (3.19, 4.42) | 3.09 (2.79, 3.34) | <0.001 |
| Hs-CRP (mg/L) | 3.4 (2.1, 5.9) | 2.1 (1.7, 3.3) | <0.001 |
| Hypertension | 119 (73.5) | 75 (69.4) | 0.473 |
| Diabetes mellitus | 42 (25.9) | 22 (20.4) | 0.293 |
| Dyslipidaemia | 67 (41.4) | 62 (57.4) | 0.010 |
| Smokers | 73 (45.1) | 22 (20.4) | <0.001 |
| Alcohol consumers | 32 (19.8) | 17 (15.7) | 0.402 |
| Hypertension med use | 40 (33.6a) | 31 (41.3a) | 0.277 |
| Diabetes med use | 21 (50.0b) | 14 (63.6b) | 0.615 |
| NIHSS on day 1 | 4 (2, 8) | / | / |
| mRS scores | 3 (2, 3) | / | / |
Continuous variables are expressed as the means ± standard deviations (SDs) or the medians (interquartile ranges). Categorical values are given as frequencies (percentages).
aRepresents the percentage in the hypertension population.
bRepresents the percentage in the diabetic population.
Abbreviations: LAA stroke, large-artery atherosclerotic stroke; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; FBG, fasting blood glucose; TG, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HbA1C, glycated haemoglobin; hs-CRP, high-sensitivity C-reactive protein; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale.