Table 1.
Minimal inhibitory concentration of AS-48 alone and in combination with lysozyme assayed by the microdilution method.
| Isolate | AS-48 (µg/mL) | AS-48 (µg/mL) + Lysozyme (0.40 mg/mL) | Isolate | AS-48 (µg/mL) | AS-48 (µg/mL) + Lysozyme (0.40 mg/mL) |
|---|---|---|---|---|---|
| Acne | Other sources | ||||
| P0 | 0.62 | 0.052** | P6 | 1.25 | 0.86/0.15 |
| P3 | 1.25 | 0.26 | P7 | 2.50 | — |
| P4 | 0.62 | — | P15 | 0.94 | 0.625 |
| P11 | 0.62 | 0.47 | P17 | 1.25 | 0.104** |
| P12 | 0.75 | 0.019** | P18 | 1.25 | 0.93 |
| P13 | 0.94 | 0.39 | P19 | 2.50 | 0.62 |
| P24 | 1.87 | 1.87 | P20 | 1.25 | 0.62 |
| Wound exudates | P22 | 0.62 | 0.019** | ||
| P1 | 0.94 | 0.286 | P26 | 1.25 | 0.62 |
| P10 | 1.87 | 0.62 | P27 | 0.92 | 0.065** |
| P25 | 1.25 | 0.62 | |||
Non-cooperative effect is shown underlined. **Represents the most significant MIC reductions (more than 10x). The results are representative of three or more independent experiments.