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. 2018 Jul 31;9:837. doi: 10.3389/fphar.2018.00837

FIGURE 7.

FIGURE 7

Docking results of lico A interacting with basic region leucinzipper of CHOP protein. (A) The DNA binding site surface of CHOP shown in gray cartoon representation with a solid surface. (B) Lico A represented in green color is docked into the DNA binding site surface of CHOP. (C) The dimer interface of CHOP shown in gray cartoon representation with a solid surface. (D) Lico A represented in yellow color is docked into the dimer interface of CHOP. (E) Protein-protein docking results of CHOP and C/EBPα. The C/EBPα was represented in yellow-green and the dimer-interface of CHOP was also represented in gray cartoon. (F) A proposed scheme for lico A inhibiting CHOP signaling pathway.